Contraindications and DDIs

Contraindications and drug interactions1


  • DESCOVY FOR PREP® is contraindicated in individuals with unknown or positive HIV status

Drug interactions

  • Prescribing information: Consult the full Prescribing Information for DESCOVY® for more information, warnings, and potentially significant drug interactions, including clinical comments
  • Metabolism: Drugs that inhibit P-gp can increase the concentrations of TAF, a component of DESCOVY. Drugs that induce P-gp can decrease the concentrations of TAF, which may lead to loss of efficacy
  • Drugs affecting renal function: Coadministration of DESCOVY with drugs that reduce renal function or compete for active tubular secretion may increase concentrations of FTC and tenofovir and the risk of adverse reactions

Please see full Prescribing Information for DESCOVY FOR PrEP, including BOXED WARNING.

DDI=drug-drug interaction.