Guideline Recommendations


DESCOVY® for HIV-1 pre-exposure prophylaxis (PrEP) is indicated in at-risk adults and adolescents (≥35 kg) to reduce the risk of sexually acquired HIV-1 infection, excluding individuals at risk from receptive vaginal sex. HIV-1–negative status must be confirmed immediately prior to initiation.

Limitation of Use: DESCOVY FOR PrEP is not indicated in individuals at risk of HIV-1 from receptive vaginal sex because effectiveness in this population has not been evaluated.

National guidelines recommend PrEP for patients at risk of HIV1-3

What it means:

A Grade A recommendation by the USPSTF is defined as a recommendation of a specific service where USPSTF considers there to be a high certainty that the net benefit is substantial.1

Other organizations that recommend PrEP include:


American College Health Association

ACHA is an organization dedicated to promoting healthy campus communities through advocacy, education, and research.2,4


National HIV/AIDS Strategy

The NHAS is a national 5-year plan that details principles, priorities, and actions to guide a coordinated response to the HIV epidemic.3

Health guidelines recommend using PrEP and emphasize the importance of counseling on adherence and HIV‑1 risk-reduction strategies.5

Use DESCOVY® for HIV-1 PrEP to reduce the risk of HIV as part of a comprehensive prevention strategy to reduce the risk of STIs.

STI=sexually transmitted infection.